Author: Brian Ferguson

https://www.sciencefestival.cam.ac.uk/ What a great opportunity to talk to the public about the work we do at the Department of Pathology! We had a fabulous time making germs and antibody models …

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Christmas Brunch 2017 @ The Old Bicycle Shop

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Delphine’s Birthday Dinner at Emmanuel Collage

Happy Birthday, Delphine!

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Lab trip 2017

Our annual traditional joint Ferguson and Smith Lab trip took place in Snowdonia.

News

Brian Ferguson@viropractorRT @Dani6020: There is a lot of discussion about pre-existing immunity against SARS-CoV-2. Here is a great summary about the knowns and unk…09 July 2020

Brian Ferguson@viropractorRT @ScienceMagazine: Expanding the breadth of #immunology to include more species and environments could benefit biomedical research. Learn…09 July 2020

Brian Ferguson@viropractorRT @andymoz78: It’s not the lockdown but the virus (and lack of control of that virus) that is harming the economy- exhibit 132👇08 July 2020

Brian Ferguson@viropractorRT @carlzimmer: Sweden Has Become the World’s Cautionary Tale nytimes.com/2020/07/07/bus…08 July 2020

Brian Ferguson@viropractorRT @pathogenomenick: Nice to see the structure of the R10 pore used by @nanopore ! twitter.com/naturebiotech/…07 July 2020

Brian Ferguson@viropractorRT @JeremyFarrar: It was clear that Asymptomatic transmission #COVIDー19 was a strong possibility in mid-January, confirmed in February. Sta…07 July 2020

Brian Ferguson@viropractor“Economic growth is frequently presented as the engine for eradicating poverty but the primary beneficiaries are of… twitter.com/i/web/status/1…07 July 2020

Brian Ferguson@viropractorRT @bealelab: In the very large Spanish serosurvey, about 1/3 were asymptomatic. The “78% asymptomatic” from a smaller but well-conducted s…07 July 2020

Brian Ferguson@viropractorRT @BenjaminMeyer85: 1. Since there was a huge discussion about T-cell mediated immunity following the Lancet comment on seroprevalence by…07 July 2020

Brian Ferguson@viropractorRT @rlmcelreath: Cats reacting to bad COVID-19 models, a short thread. [This is beneath me but I really need this right now let me have thi…06 July 2020

Brian Ferguson@viropractorData from Spain. Completely clear: "In light of these findings, any proposed approach to achieve herd immunity thro… twitter.com/i/web/status/1…06 July 2020

Brian Ferguson@viropractorRT @TheLancet: NEW—First nationwide population-based study presents seroprevalence estimates of antibodies against SARS-CoV-2 at national a…06 July 2020

Brian Ferguson@viropractorRT @EckerleIsabella: Our comment on #SARSCoV2 seroprevalence in #COVID19 hotspots @TheLancet - even in severely affected areas, vast majori…06 July 2020

Brian Ferguson@viropractorRT @mbeckett: The trillion dollar question. Why are COVID cases increasing while deaths are decreasing? The answer is simple. It's called S…05 July 2020

Brian Ferguson@viropractorRT @PeterHotez: I can’t understand why everyone in the White House is so wimpy. It’s not that hard. Every nation except us has stopped #COV…05 July 2020

Brian Ferguson@viropractorAmen. pic.twitter.com/4y2VxJDEyO05 July 2020

Brian Ferguson@viropractorRT @AstroKatie: We are all 100% willing to do our jobs in ways that don’t involve exchanging virus-laden air with rooms full of young peopl…05 July 2020

Brian Ferguson@viropractorRT @stephrstephr: Please RT: Postdoc available at NIH in Montana to work on the dynamic arthropod-pathogen-host interaction at the cutaneou…05 July 2020

Brian Ferguson@viropractorRT @LGMartelotto: Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc. https:…05 July 2020

Brian Ferguson@viropractorVery interesting report of disease tolerence in COVID-19, evidencing that severe pathology is driven by virus-indep… twitter.com/i/web/status/1…05 July 2020

Brian Ferguson@viropractorRT @doctor_oxford: There we are. @RishiSunak swore he would give the NHS whatever it needs to fight coronavirus. Apparently those were mere…05 July 2020

Brian Ferguson@viropractorRT @EricTopol: Belgium was the worst-hit country per capita in Europe. They did systematic testing for #SARSCoV2 in long-term care faciliti…05 July 2020

Brian Ferguson@viropractorApart from the horror of so many COVID-19 deaths, a theme is the potentially very long-term (and in some cases irr… twitter.com/i/web/status/1…05 July 2020

Brian Ferguson@viropractorRT @ScienceMagazine: Unlike most antibodies to #SARSCoV2, which target the virus spike protein's receptor binding domain, a newly discovere…05 July 2020

Brian Ferguson@viropractorRT @kakape: I’ve been following the research on experimental therapies to treat #covid19 from the beginning and in the last month the three…04 July 2020

Brian Ferguson@viropractorRT @NereaIrigoyen: Physical distancing and wear a face covering if you don’t want to spend another four months without going to the pub!!!…04 July 2020

Brian Ferguson@viropractorRT @andymoz78: Sadly such insight is also somewhat lacking in England too- control of the virus is the most important factor in restoring t…04 July 2020

Brian Ferguson@viropractorRT @3DiMMUNE: pre-existing CD8 T cell immunity eliminate Cas9+ gene-edited liver cells in mice. #CRISPR AAV-CRISPR Gene Editing Is Negate…03 July 2020

Brian Ferguson@viropractorRT @NerdyNic: “The taverns are full of gadabouts making merry this eve. And though I may press my face against the window like an urchin at…03 July 2020

Brian Ferguson@viropractorRT @ArnaudjLegrand: Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity 👉6-thio-dG (6TG) ➡️telomere-associated DNA damage 👉6T…03 July 2020

Brian Ferguson@viropractorRT @_chris_brooke: Happy to share our study in @PLOSPathogens looking at the complex interplay between viral and host transcription pattern…02 July 2020

Brian Ferguson@viropractorStraw poll for parents of young kids. On a scale of 1 to 10, how exhausted are you?02 July 2020

Brian Ferguson@viropractorBlimey. Those are some big %’s. Warning for the Uk where bars and pubs are reopening on sat. twitter.com/MSNBC/status/1…01 July 2020

Brian Ferguson@viropractorRT @alanmcn1: Also supports idea of low titre = low to zero transmission. Transmission dynamics of asymptomatic individuals is single bigge…01 July 2020

Brian Ferguson@viropractorRT @LabListon: I am really thrilled to release #AutoSpill onto @biorxivpreprint. It is a novel method for applying compensation to #flowcyt…01 July 2020

Brian Ferguson@viropractorRT @AdamRutherford: ❤️ 🇳🇿 🧬 Imagine what it must be like to have leadership like this, a PM who truly and sincerely values science and sci…01 July 2020

Brian Ferguson@viropractorRT @EckerleIsabella: Our publication on culture-competent #SARSCoV2 in children with #COVID19 is now online: High viral loads & isolation o…01 July 2020

Brian Ferguson@viropractorRT @DZhivaki: Great paper by Arlene Sharpe &colleagues showing that PD1 deficiency augments early effector responses but results in defecti…30 June 2020

Brian Ferguson@viropractorRT @NJTemperton: 2yr Postdoctoral position available on SARS-CoV-2 immuno-pathogenesis available in @ViralPseudotype funded by @wellcometru…30 June 2020

Brian Ferguson@viropractorRT @pgeorgiou_ic: We’ve done it! The first handheld molecular diagnostic for rapid detection of SARS-CoV-2! Validation results - average de…30 June 2020

Brian Ferguson@viropractorThe pnas contributor track should be replaced by a pnas-branded preprint server so members can just dump whatever c… twitter.com/i/web/status/1…30 June 2020

Brian Ferguson@viropractorpostdoc opportunity @CamPathology. Get involved 🦠🔬👇👇 twitter.com/AtomicVirology…30 June 2020

Brian Ferguson@viropractorRT @MoyneFlu: Here is a good thread explaining the reality of the threat posed by the G4 swine influenza virus. In short, it's something es…30 June 2020

Brian Ferguson@viropractorRT @bxv_imm: Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19 dlvr.it/RZckHD29 June 2020

Brian Ferguson@viropractorBeautiful! twitter.com/VanniniLab/sta… pic.twitter.com/s6XkI1Qslh29 June 2020

Brian Ferguson@viropractorMore T cell immunity w/o antibody responses in COVID patients. Looks like T cell analysis will show higher % people… twitter.com/i/web/status/1…29 June 2020

Brian Ferguson@viropractorRT @CyrilPedia: 'Here, we stimulated PBMCs from ten COVID-19 patients with ARDS, collected up to three weeks after admission to the intensi…29 June 2020

Brian Ferguson@viropractorRT @_b_meyer: A great Tweetorial about the Phosphorylation Landscape by #SARSCoV2 infected cells. 👇28 June 2020

Brian Ferguson@viropractorRT @andymoz78: It’s not the lockdown that is killing the economy, it’s a failure to control the virus- exhibit number 324 👇 https://t.co/D1…28 June 2020

Brian Ferguson@viropractorThe thing about proteins is they move around way more than people give them credit for. Same as with plants, just t… twitter.com/i/web/status/1…28 June 2020

Brian Ferguson@viropractorFabulous thread 👇🏽 twitter.com/vectorgen/stat…28 June 2020

Brian Ferguson@viropractorRT @DrAlysonHanish: Just a reminder, this pandemic continues to impact academics with young/school age kids. This has not disappeared. Scho…27 June 2020

Brian Ferguson@viropractorSome more data showing mild covid cases don’t always seroconvert. Robust T cell responses though, which is somewhat… twitter.com/i/web/status/1…27 June 2020

Brian Ferguson@viropractorRT @doctorveera: This study maps eQTLs in 6 fibroblast and 4 iPSC cell types using scRNA-seq and demonstrates that eQTLs are highly cell-ty…27 June 2020

Brian Ferguson@viropractorThis is great! Imagine there are >100,000 papers on p53 but zero knowledge of about 40% of the global proteome. twitter.com/MartT_babraham…27 June 2020

Brian Ferguson@viropractorRT @richdavisphd: What does a mask do? Blocks respiratory droplets coming from your mouth and throat. Two simple demos: First, I sneezed,…27 June 2020

Brian Ferguson@viropractorRT @JanetDeaneLab: We're hiring! Come and join our team studying lipid-protein complexes in neurodegenerative disease. @TheCIMR https://t.c…27 June 2020

Brian Ferguson@viropractorRT @mjwsim: This paper proposes 4 (four!) new ligands for NCR1 (NKp46) and they’re CD4, SIGLEC6, SIGLEC7 and SIGLEC8.27 June 2020

Brian Ferguson@viropractorRT @WTKLAB: Looks like there will be costed extensions and support for some UKRI grants. That's welcome news!27 June 2020

Brian Ferguson@viropractorRT @Babak_Javid_Lab: Death rates among hospitalized patients in UK now 6x lower than at peak in March/April. Lots of reasons including bet…26 June 2020

Brian Ferguson@viropractorRT @florian_krammer: 1) A lot of people see cases rising while deaths are going down in the US. Somebody who did not like my tweet earlier…26 June 2020

Brian Ferguson@viropractorSome more data re. masks preventing COVID spread. Like some parts of the US, the UK is not yet catching on. twitter.com/jduchneskie/st…25 June 2020

Brian Ferguson@viropractorWorth noting that the German coronavirus tracing app is open source so could already have been implemented in the U… twitter.com/i/web/status/1…25 June 2020

Brian Ferguson@viropractorRT @HaselbachLab: Our cryo EM structure of the mysterious E3 Ligase RNF213 has just been published. This was wonderful collaboration with @…23 June 2020

Brian Ferguson@viropractorRT @clausen_lab: Excited to share our first cryoEM work, the structure of the mysterious E3 giant RNF213. elifesciences.org/articles/56185 Kudos to…23 June 2020

Brian Ferguson@viropractorRT @bart_lambrecht: Must read for all interested in asthma and type 2 immunity : Serum amyloid A is a soluble pattern recognition receptor…23 June 2020

Brian Ferguson@viropractorRT @McGovernLab: We're looking for a postdoc to join our team, to research macrophages at the maternal-fetal interface. For more details, p…23 June 2020

Brian Ferguson@viropractorRT @cshperspectives: RECOVERY trial showing dexamethasone reduces mortality in #COVID19 now on medRxiv! medrxiv.org/content/10.110… https://t.…22 June 2020

Brian Ferguson@viropractorRT @laoneill111: Further good news on steroids in severe COVID19 patients. 2 more studies agree with dexamethasone study protecting signifi…22 June 2020

Brian Ferguson@viropractorRT @ZJAyres: Mental health through the various stages of Academia, from undergrad ➡️PhD ➡️ Postdoc ➡️ faculty, illustrated through posters.…21 June 2020

Brian Ferguson@viropractorRT @hristova_dayana: My first week in the lab finished yesterday! ✨👩‍🔬 I have missed the #lab and it was great to be back ☺️ @CamPathology…21 June 2020

Brian Ferguson@viropractorRT @EricTopol: #COVID19 and the gender inequity in academics pnas.org/content/pnas/e… @PNASNews @MalischPhd and colleagues @AAUW and a bro…21 June 2020

Brian Ferguson@viropractorIt never was. Not for one second. twitter.com/techreview/sta…21 June 2020

Brian Ferguson@viropractorIf it’s good enough for POTUS candidate selection, then I think our next faculty recruitment should focus on assess… twitter.com/i/web/status/1…21 June 2020

Brian Ferguson@viropractorRT @BioMickWatson: Does this hold up?21 June 2020

Brian Ferguson@viropractorRT @RogueRad: Lots of chest CTs with the history “COVID-19 survivor.” Lungs look mangled21 June 2020

Brian Ferguson@viropractorRT @c_drosten: Hi! This is a typical bias in symptoms-triggered household studies. Children are mostly asymptomatic so are mostly missed as…21 June 2020

Brian Ferguson@viropractorRT @demetriachavon: A little wake up call for all of you not wearing masks: My cousin checked into the hospital Tuesday morning for body a…21 June 2020