Latest publications:
Enhanced efficacy of vaccination with vaccinia virus in old vs. young mice Evgeniya V. Shmeleva, Geoffrey L. Smith and Brian J. Ferguson Frontiers in Immunology, Volume 10: 1780 |
2019 |
ISG15-Induced IL-10 Is a Novel Anti-Inflammatory Myeloid Axis Disrupted during Active Tuberculosis Paula Fernandes dos Santos, Johan Van Weyenbergh, Murilo Delgobo, Daniel de Oliveira Patricio, Brian J. Ferguson, Rodrigo Guabiraba, Tim Dierckx, Soraya Maria Menezes, André Báfica and Daniel Santos Mansur Journal of Immunology, Volume 200(2) |
2018 |
The Non-Homologous End Joining Protein PAXX Acts to Restrict HSV-1 Infection Ben J. Trigg, Katharina B. Lauer, Paula Fernandes dos Santos, Heather Coleman, Gabriel Balmus, Daniel S. Mansur and Brian J. Ferguson Viruses, Volume 9(11) |
2017 |
Genome-wide analyses reveal a highly conserved Dengue virus envelope peptide which is critical for virus viability and antigenic in humans RC Fleith, FP Lobo, PF dos Santos, MM Rocha, J Bordignon, DM Strottmann, DO Patricio, WR Pavanelli, M Lo Sarzi, CN Dos Santos, BJ Ferguson, DS Mansur Scientific Reports 6, Article number: 36339 |
2016 |
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation J Zinngrebe, E Rieser, L Taraborrelli, N Peltzer, T Hartwig, H Ren, I Kovács, C Endres, P Draber, M Darding, S von Karstedt, J Lemke, B Dome, M Bergmann , BJ Ferguson*, H Walczak* J Experimental Medicine (In Press) |
2016 |
Increased attenuation but decreased immunogenicity by deletion of multiple vaccinia virus immunomodulators RP Sumner, H Ren, BJ Ferguson, GL Smith Vaccine Volume 34, Pages 4827–4834 |
2016 |
The Schistosoma mansoni T2 ribonuclease omega-1 modulates inflammasome-dependent IL-1beta secretion in macrophages BJ Ferguson, S Newland, SE Gibbs, P Tourlomousis, P Fernandes dos Santos, MN Patel, SW Hall, H Walczak, G Schramm, H Haas, DW Dunne, A Cooke, and P Zaccone International Journal for Parasitology Volume 45, Issue 13 Pages 809–813 |
2015 |
Functions of DNA damage machinery in the innate immune response to DNA virus infection BJ Trigg and BJ Ferguson Current Opinion in Virology Volume 15, Pages 56–62 |
2015 |
International Union of Basic and Clinical Pharmacology. XCVI. Pattern Recognition Receptors in Health and Disease CE Bryant, S Orr, BJ Ferguson, MF Symmons, JP Boyle, and TP Monie Pharmacological Reviews vol. 67 no. 2 462-504 |
2015 |
Enhancement of CD8+ T‐cell memory by removal of a vaccinia virus NF‐κB inhibitor H Ren, BJ Ferguson, C Maluquer de Motes, RP Sumner, L Harman, GL Smith Immunology 145 (1), 34-49 |
2015 |
The role of shed placental DNA in the systemic inflammatory syndrome of pre-eclampsia JDR Hartley, BJ Ferguson, A Moffett American Journal of Obstetrics and Gynecology Volume 213, Issue 3, Pages 268–277 |
2015 |
Intracellular sensing of viral DNA by the innate immune system DS Mansur, GL Smith, BJ Ferguson Microbes and Infection 16 (12), 1002-1012 |
2014 |
Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo CH Ku, BJ Ferguson J Vis Expts e51593-e51593 |
2014 |
A mechanism for the inhibition of DNA-PK mediated DNA sensing by a virus NE Peters, BJ Ferguson, M Mazzon, AS Fahy, E Krystofinska, R Arribas-Bosacoma, LH Pearl, H Ren, GL Smith PloS Pathogens 9(10): e1003649 |
2013 |
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity GL Smith, CTO Benfield, CM de Motes, M Mazzon, SWJ Ember, BJ Ferguson, RP Sumner Journal of General Virology, 94: 2367-2392 |
2013 |
A mechanism for induction of a hypoxic response by vaccinia virus M Mazzon, NE Peters, C Loenarz, EM Krysztofinska, SWJ Ember, BJ Ferguson, GL Smith Proceedings of the National Academy of Sciences, 110 (30), 12444-12449 |
2013 |
Vaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulence BJ Ferguson, CTO Benfield, H Ren, VH Lee, GL Frazer, P Strnadova, RP Sumner, GL Smith Journal of General Virology, 94 (9), 2070-2081 |
2013 |
Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence DS Mansur, CM de Motes, L Unterholzner, RP Sumner, BJ Ferguson, H Ren, P Strnadova, AG Bowie, GL Smith PLoS pathogens 9 (2), e1003183 |
2013 |
Vaccinia virus protein C4 inhibits NF-κB activation and promotes virus virulence SWJ Ember, H Ren, BJ Ferguson, GL Smith Journal of General Virology 93 (Pt 10), 2098-2108 |
2012 |
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity BJ Ferguson, DS Mansur, NE Peters, H Ren, GL Smith eLife Sciences 1 e00047 |
2012 |
Mapping the IκB kinase β (IKKβ)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKβ-mediated activation of NF-κB CTO Benfield, DS Mansur, LE McCoy, BJ Ferguson, MW Bahar, AP Oldring, JM Grimes, DI Stuart, SC Graham, GL Smith Journal of Biological Chemistry 286 (23), 20727-20735 |
2011 |
Vaccinia protein F12 has structural similarity to kinesin light chain and contains a motor binding motif required for virion export GW Morgan, M Hollinshead, BJ Ferguson, BJ Murphy, DCJ Carpentier, GL Smith PLoS pathogens 6 (2), e1000785 |
2010 |
PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool W Li, BJ Ferguson, WT Khaled, M Tevendale, J Stingl, V Poli, T Rich, P Salomoni, CJ Watson Proceedings of the National Academy of Sciences 106 (12), 4725-4730 |
2009 |
Death in the AIRE BJ Ferguson, A Cooke, P Peterson, T Rich Trends in immunology 29 (7), 306-312 |
2008 |
New insights into the role of PML in tumour suppression P Salomoni, BJ Ferguson, AH Wyllie, T Rich Cell research 18 (6), 622-640 |
2008 |